Showing posts with label multiple sclerosis. Show all posts
Showing posts with label multiple sclerosis. Show all posts

Monday, February 29, 2016

How to cool the flames wrecking havoc on your health . . .




Several chronic diseases are mediated by your
body’s inflammatory response. Conditions such as multiple sclerosis, depression, anxiety, arthritis, obstructive pulmonary disease, cardiovascular disease and even obesity are mediated by chronic inflammation.1, 2,3 When you experience an acute infection or sustain an injury to your body, your immune system mobilizes an inflammatory response to neutralize the infectious agent or initiate a healing response.  Your body cannot combat acute infections or heal damaged tissues without inflammation. Conditions like heart disease, however, are the outcome of low grade, “silent” inflammation that is systemic and chronic.  


Many over the counter and pharmaceutical medications (e.g., NSAIDs like ibuprofen, COX-2 inhibitors such as Celebrex) exist to reduce inflammation in your body.   While these drugs do lower inflammation in your body, they bring with them several side effects (i.e., ranging from mild skin reactions and stomach ulcers to more serious conditions such as heart attacks, thrombosis and strokes).  Thankfully, you can balance your immune system and modulate your body’s inflammatory response by changing your lifestyle.


Evaluating your body's response to and avoiding common food allergens (i.e., shellfish, soy, dairy, corn, gluten, peanuts, citrus, mold, fermented foods) that set off an alarm in your immune system as well as  balancing your ratio of omega 6 to omega 3 fatty acids will go a long way towards balancing your body’s inflammatory response.  Your body’s inflammatory system is regulated by your immune system and hormone-like substances known as prostaglandins.  

Prostaglandins are enzymatically derived from fatty acids and exert their physiological effect at localized tissue sites.  Omega 6 fatty acids act as the building blocks for inflammatory prostaglandins.  Omega 6 fatty acids are found primarily in nuts and seeds, processed vegetable oils, grains, legumes and conventionally raised animal foods.   Omega 3 fatty acids help your body to produce anti-inflammatory prostaglandins.  Rich food sources include small cold water, fatty fish, grass fed and pasture raised animals, dark green, leafy vegetables and some nuts and seeds.  Ideally, you will eat a 3:1 to 1:1 ratio of omega 6 to omega 3 fatty acids.  Unfortunately, the average American eats very SADly (Standard American Diet) and consumes a 16:1 ratio of omega 6 to omega 3 fatty acids.4


In order to decrease your levels of systemic inflammation, prevent many chronic diseases and optimize your health, you must reduce your intake of unnecessary omega 6 fatty acids.  Processed vegetable oils used for cooking and in most processed foods are often high in omega 6 fatty acids.  Instead, cook with animal fats or plant sources of saturated fat that are more stable and do not oxidize easily.  Tallow, suet, butter or ghee (grass fed) and coconut oil are healthy choices.  In addition, make sure you increase your intake of long chain omega 3 fatty acids (i.e., EPA and DHA) by including food rich sources at least twice a week.  While long chain omega 3 fatty acids have powerful anti-inflammatory effects in the body, plant sources of medium chain omega 3 fatty acids such as ALA are important for optimal health.  Nuts, seeds and leafy dark greens are rich sources of medium chain omega 3 fatty acids.  Make sure you include several servings a week.


To reduce systemic inflammation and optimize your health, you must also reduce your intake of refined and starchy carbohydrates.  Excessive consumption of quickly digested carbohydrates (i.e., high glycemic index) contributes to the production of pro inflammatory Advanced Glycation End products (AGEs) that wreak havoc inside your body.  AGEs are formed when simple sugar molecules bind to protein or fat without the enzymes necessary to control the reaction.  You can also reduce AGEs by using low heat cooking methods such as steaming or light sautéing and reducing your consumption of animal proteins that have been browned or charred.


Regular exercise can also help to further reduce systemic inflammation by enhancing your body’s production of the anti-inflammatory, cytokine interleukin (IL)-10.5 Cytokines are chemical messengers that work to orchestrate your body’s immune system and inflammatory response.  Aim to exercise for 30 to 45 minutes, four to five times per week to achieve optimal results.    And, remember to have fun and play with your workouts.  Vary your workouts and try adding brief, intense exercise routines a couple times a week.



Healthy Fats

  • Long chain omega 3 fatty acids: grass fed, pasture raised animals or wild caught, cold water, small fish. (e.g., sardines, herring, anchovies, sock eye salmon, bison, beef, venison, lamb).

  • Medium chain omega 3 fatty acids: dark leafy greens, walnuts, seeds (chia, flax, hemp, sacha inchi).

  • Omega 6 fatty acids: nuts, seeds (black currant, chia, flax, hemp, sesame, sacha inchi, pumpkin).

  • Saturated fats: grass fed, pasture raised animals, butter, ghee, tallow, suet, coconuts.

  • Monounsaturated fats: avocados, olives, grass fed, pasture raised animals, nuts (almonds, macadamia, cashews).

To your health,

Dr. Sandoval

To learn more about how working with a psychologist and holistic health coach can help you to enhance your health and well-being, call or email Dr. Sandoval to schedule a free consultation. 
  1. Perry, VH.   "The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease." Brain, Behavior, and Immunity. (2004), 18 (5): 407–41. 
  2. Salim, S, Chugh, G, Asghar, M.  "Inflammation in anxiety." Advances in Protein Chemistry and Structural Biology. (2012.) (88):1–25. doi:10.1016/B978-0-12-398314-5.00001-5. 
  3. Sin, DD and Paul Man, SF.   "Why Are Patients With Chronic Obstructive Pulmonary Disease at Increased Risk of Cardiovascular Diseases? The Potential Role of Systemic Inflammation in Chronic Obstructive Pulmonary Disease." Circulation. (2003), 107:1514-1519. 
  4. Simopoulos, AP. "The importance of the ratio of omega-6/omega-3 essential fatty acids." Biomedicine and Pharmacotherapy. (2002), 56(8):365-79.
  5. Ostrowski, K, Rohde, T, Asp, S, Schjerling, P, and Pedersen, BK.  "Pro-and anti-inflammatory cytokine balance in strenuous exercise in humans." Journal of Physiology. (1999), 15; 515(Pt 1): 287–291.

The information, published and/or made available through the www.fullofradiance.com website, is not intended to replace the services of a physician, nor does it constitute a physician-patient relationship. This blog is for informational purposes only and is not a substitute for professional medical advice. You should not use the information in this post for diagnosing or treating a medical or health condition. You should consult a physician in all matters relating to your health, particularly in respect to any symptoms that may require diagnosis or medical attention.  Any action on the reader’s part in response to the information provided in this blog is at the reader’s discretion.   

Monday, January 18, 2016

How to build a better brain with physical exercise.

If you’re like most people these days, you probably know that regular exercise does your
body good.  You know that exercise can help you gain physical strength, lose weight, improve your cardiovascular endurance and obtain that “beach body” that you’ve been dreaming about in your sleep.  You may also know about the various benefits of exercise for your health such as how it will help you to lower your cholesterol, blood pressure and blood sugar levels.   It certainly is all over the news these days on T.V., online and media advertisements.  You rarely hear, however, about how the benefits of exercise extend far beyond building gaining strength and your heart health.  More than just having that  “beach body” you desire and being great for your heart, exercise is important for preserving and building your most important muscle – your brain!


Several human and animal studies strongly suggest that exercise induces neurogenesis (i.e., the production of new brain neurons and synaptic connections), protects your brain against strokes, and helps you to preserve your memories to avoid having those senior moments.1,2,3  Exercise promotes the production of brain derived neurotropic factor (BDNF) and other nerve growth factors, helps to raise the circulating levels of proteins like FNDC5 and helps to stimulate angio­gen­e­sis (i.e., the formation of new blood vessels that help  to improve cerebral blood flow) so it will help to repair damaged brain cells.4   Many of these effects have been demonstrated in people with Parkinson’s disease and Multiple Sclerosis.5, 6



So if you’re concerned about preserving your brain health and want to avoid having those  regrettable senior moments, it is important that you exercise regularly.  Although the research suggests that more vigorous exercise like sprinting seems to lead to greater benefits, simply walking briskly 3-4 times a week for 30 minutes will help you to build a better brain. 


  
To your health,


Dr. Sandoval


To learn more about how working with a psychologist  and holistic health coach can help you to enhance your health and well being, call or email Dr. Sandoval to schedule a free consultation.


  1.  Cotman, CW &  Berchtold, NC. “Exercise: a behavioral intervention to enhance brain health and plasticity.” TRENDS in Neurosciences.  (2002). 25 (6), 295-301. 
  2. Hayes, K, Sprague, S, Guo, M, Davis, W, Friedman, A, Kumar, A, et al. “Forced, not voluntary, exercise effectively induces neuroprotection in stroke.”  Acta Neuropathologica. (2008)115, 289–296. 
  3. Praag,H, Kempermann, G & Gage, FH. “Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus” Nature Neuroscience. (1999). 2, 266 – 270. 
  4. Huh, JY, Panagiotou, G, Mougios, V, Brinkoetter, M, Vamvini, MT, Schneider, BE, et al.   “FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise.”  Metabolism. (2012) 61 (12), 1725-38. 
  5.  Ahlskog, JE.   “Does vigorous exercise have a neuroprotective effect in Parkinson disease?” Neurology.  (2011). 77 (3), 288 – 294. 
  6.  Gold, SM, Schulz, KH, Hartmann, S, Mladek, M, Lang, UE, Hellweg, R, et al. Basal serum levels and reactivity of nerve growth factor and brain-derived neurotrophic factor to standardized acute exercise in multiple sclerosis and controls  Journal of Neuroimmunology. . (2003). 138, (1–2), 99-105.


The information, published and/or made available through the www.fullofradiance.com website, is not intended to replace the services of a physician, nor does it constitute a physician-patient relationship. This blog is for informational purposes only and is not a substitute for professional medical advice. You should not use the information in this post for diagnosing or treating a medical or health condition. You should consult a physician in all matters relating to your health, particularly in respect to any symptoms that may require diagnosis or medical attention.  Any action on the reader’s part in response to the information provided in this blog is at the reader’s discretion.


Wednesday, June 17, 2015

How your brain heals with exercise . . .

If you’re like most people these days, you
probably know that regular exercise does your body good.  You know that exercise can help you gain physical strength, lose weight, improve your cardiovascular endurance and obtain that summer “beach body” that you’ve been dreaming about while sleep.  You may also know about the various benefits of exercise for your health such as how it will help you to lower your cholesterol, blood pressure and blood sugar levels.   It certainly is all over the news these days on T.V., online and media advertisements.  However, you rarely hear about how exercise is a critical element in helping you to heal your brain.  Beyond building a better “beach body” and being great for your heart, exercise is important for  protecting, building and healing  your most important muscle – your brain!

Several human and animal studies strongly suggest that exercise induces neurogenesis (i.e., the production of new brain neurons and synaptic connections), protects your brain against strokes, and helps you to preserve your memories to avoid having those senior moments.1,2,3,4  Exercise promotes the production of brain derived neurotropic factor (BDNF) and other nerve growth factors like glial cell derived neurotropic factor (GDNF), helps to raise the circulating levels of proteins like FNDC5 and helps to stimulate angio­gen­e­sis (i.e., the formation of new blood vessels that help  to improve cerebral blood flow) so it will help to repair damaged brain cells.5   Many of these effects have been demonstrated in people with Alzheimer's disease, Parkinson’s disease and Multiple Sclerosis.2,6,7 
So if you’re concerned about preserving your brain health and want to avoid having those  regrettable senior moments, it is important that you exercise regularly.  Although the research suggests that more vigorous exercise like sprinting and doing tabata training  seems to lead to greater benefits, simply walking briskly with conscious awareness (mindful walking) 3-4 times a week for 30 minutes will help you to build a better brain.  

To your health,

Dr. Sandoval


To learn more about how working with a psychologist  and holistic health coach can help you to enhance your health and wellbeing, call or email Dr. Sandoval to schedule a free consultation.

  1. Cotman, CW &  Berchtold, NC. “Exercise: a behavioral intervention to enhance brain health and plasticity.” TRENDS in Neurosciences.  (2002). 25 (6), 295-301. 
  2. Doidge, N. The Brain's Way of Healing: Remarkable Discoveries and Recoveries from the Frontiers of Neuroplasticity.  (2015).
  3. Hayes, K, Sprague, S, Guo, M, Davis, W, Friedman, A, Kumar, A, et al. “Forced, not voluntary, exercise effectively induces neuroprotection in stroke.”  Acta Neuropathologica. (2008)115, 289–296. 
  4. Praag,H, Kempermann, G & Gage, FH. “Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus” Nature Neuroscience. (1999). 2, 266 – 270. 
  5. Huh, JY, Panagiotou, G, Mougios, V, Brinkoetter, M, Vamvini, MT, Schneider, BE, et al.   “FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise.”  Metabolism. (2012) 61 (12), 1725-38. 
  6.  Ahlskog, JE.   “Does vigorous exercise have a neuroprotective effect in Parkinson disease?” Neurology.  (2011). 77 (3), 288 – 294. 
  7. Gold, SM, Schulz, KH, Hartmann, S, Mladek, M, Lang, UE, Hellweg, R, et al. Basal serum levels and reactivity of nerve growth factor and brain-derived neurotrophic factor to standardized acute exercise in multiple sclerosis and controls  Journal of Neuroimmunology. (2003). 138, (1–2), 99-105.

The information, published and/or made available through the www.fullofradiance.com website, is not intended to replace the services of a physician, nor does it constitute a physician-patient relationship. This blog is for informational purposes only and is not a substitute for professional medical advice. You should not use the information in this post for diagnosing or treating a medical or health condition. You should consult a physician in all matters relating to your health, particularly in respect to any symptoms that may require diagnosis or medical attention.  Any action on the reader’s part in response to the information provided in this blog is at the reader’s discretion.


Wednesday, March 25, 2015

Why less is more with your body . . .



If you’re like many people and are trying to
lose weight or improve your health, you may think that you have to follow a restrictive diet and exercise to burn the calories.  While this approach may work for some people in the short term, the reality is that most people who diet end up gaining all the weight that they have lost within 5 years. 


Similarly, you may be trying to improve your health and believe that taking many supplements, using natural products and exercising regularly will help you to raise your body’s defenses and physical health.   While there are certainly some key supplements that you want to include in your lifestyle (e.g., a quality multivitamin, fish oil, vitamin D, Magnesium, and probiotics), there are several problems with this approach.  


By diverting your attention from what is important to you, your focus will be on what is wrong with your body to the exclusion of all the other domains in your life (e.g., relationships, career, community, service, leisure, spirituality) that enrich you with meaning and purpose.  Moreover, many of these behaviors are different forms of avoidance and may be masking the root cause of your illness and DIS-ease. 


Over-training physically, eating under stress, being dissatisfied with your relationships, feeling that you are “stuck” at your job that you only hold on to pay your bills all sound “alarms” to your sympathetic nervous system and will raise your cortisol levels dramatically.  This alone can directly contribute to adrenal fatigue, enhanced intestinal permeability (i.e., leaky gut syndrome) and low stomach acid production, which can open the gateway to diseases such as IBS, rheumatoid arthritis, diabetes and multiple sclerosis.   


So rather than continue with these unproductive and potentially harmful behaviors, learn to shift gears and focus on what truly matters to you in your life.  And while you’re at it, make sure that you get the basics to good health down pat (i.e., adequate sleep and rest, savoring and enjoying whole unprocessed foods, nourishing the relationships with the people who are important to you, developing a spiritual practice, spending time outside in nature consistently).

To your health,

Dr. Sandoval

To learn more about how working with a psychologist and holistic health coach can help you to enhance your health and well-being, call or email Dr. Sandoval to schedule a free consultation.